(Peer-Reviewed) Spatiotemporal hemodynamic monitoring via configurable skin-like microfiber Bragg grating group
Hengtian Zhu 朱衡天 ¹, Junxian Luo 罗俊贤 ², Qing Dai 戴庆 ³, Shugeng Zhu 朱衡天 ¹, Huan Yang 杨欢 ¹, Kanghu Zhou 周康虎 ¹, Liuwei Zhan 詹鎏玮 ¹, Biao Xu 徐标 ³, Ye Chen 陈烨 ¹, Yanqing Lu 卢延庆 ¹, Fei Xu 徐飞 ¹
¹ College of Engineering and Applied Sciences and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210023, China
中国 南京 南京大学现代工程与应用科学学院 人工微结构科学与技术协同创新中心
² School of Physics, Nanjing University, Nanjing 210023, China
中国 南京 南京大学物理学院
³ Department of Cardiology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing 210008, China
中国 南京 南京大学医学院附属鼓楼医院心血管内科
Systemic blood circulation is one of life activity’s most important physiological functions. Continuous noninvasive hemodynamic monitoring is essential for the management of cardiovascular status. However, it is difficult to achieve systemic hemodynamic monitoring with the daily use of current devices due to the lack of multichannel and time-synchronized operation capability over the whole body.
Here, we utilize a soft microfiber Bragg grating group to monitor spatiotemporal hemodynamics by taking advantage of the high sensitivity, electromagnetic immunity, and great temporal synchronization between multiple remote sensor nodes. A continuous systemic hemodynamic measurement technique is developed using all-mechanical physiological signals, such as ballistocardiogram signals and pulse waves, to illustrate the actual mechanical process of blood circulation. Multiple hemodynamic parameters, such as systemic pulse transit time, heart rate, blood pressure, and peripheral resistance, are monitored using skin-like microfiber Bragg grating patches conformally attached at different body locations.
Relying on the soft microfiber Bragg grating group, the spatiotemporal hemodynamic monitoring technique opens up new possibilities in clinical medical diagnosis and daily health management.