(Peer-Reviewed) Military traumatic brain injury: a challenge straddling neurology and psychiatry
Ling-Zhuo Kong ¹, Rui-Li Zhang 张瑞丽 ¹, Shao-Hua Hu 胡少华 ¹ ² ³ ⁴ ⁵, Jian-Bo Lai 来建波 ¹ ² ³ ⁴ ⁵
¹ Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China
中国 杭州 浙江大学医学院附属第一医院精神卫生科
² The Key Laboratory of Mental Disorder's Management in Zhejiang Province, Hangzhou, 310003, China
中国 杭州 浙江省精神障碍诊疗和防治技术重点实验室
³ Brain Research Institute of Zhejiang University, Hangzhou, 310003, China
中国 杭州 浙江大学脑科学与脑医学学院
⁴ Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou, 310003, China
中国 杭州 数理心理健康浙江省工程研究中心
⁵ MOE Frontier Science Center for Brain Science and Brain-Machine Integration, Zhejiang University, Hangzhou, 310003, China
中国 杭州 浙江大学 教育部脑与脑机融合前沿科学中心
Abstract
Military psychiatry, a new subcategory of psychiatry, has become an invaluable, intangible effect of the war. In this review, we begin by examining related military research, summarizing the related epidemiological data, neuropathology, and the research achievements of diagnosis and treatment technology, and discussing its comorbidity and sequelae.
To date, advances in neuroimaging and molecular biology have greatly boosted the studies on military traumatic brain injury (TBI). In particular, in terms of pathophysiological mechanisms, several preclinical studies have identified abnormal protein accumulation, blood–brain barrier damage, and brain metabolism abnormalities involved in the development of TBI.
As an important concept in the field of psychiatry, TBI is based on organic injury, which is largely different from many other mental disorders. Therefore, military TBI is both neuropathic and psychopathic, and is an emerging challenge at the intersection of neurology and psychiatry.
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