Year
Month
(Preprint) Transplantation of a Beating Heart: A First in Human
Shengli Yin 殷胜利 ¹, Jian Rong 荣健 ², Yinghua Chen 陈颖华 ³ ⁴ ⁵, Lu Cao 曹璐 ², Yunqi Liu 刘云奇 ¹, Shaoyan Mo 莫少言 ², Hanzhao Li 李汉钊 ¹, Nan Jiang 江楠 ⁶, Mai Xiong 熊迈 ¹, Han Shi 石寒 ², Tielong Wang ³ ⁴ ⁵, Yongxu Shi 石勇序 ², Yanlin Zhu 朱艳玲 ², Mengya Liang 梁孟亚 ¹, Wei Xiong 熊炜 ⁶, Yili Chen ⁷, Guixing Xu ⁸, Xiaoxiang Chen ⁶, Xiaojun Chen 陈小俊 ⁹, Meixian Yin ³ ⁴ ⁵, Baiyun Tang 唐白云 ¹⁰, Fengqiu Gong 龚凤球 ⁹, Wenqi Huang ⁶, Yugang Dong 董吁钢 ⁷, Björn Nashan ¹¹, Stefan G Tullius ¹², Zhiyong Guo 郭志勇 ³ ⁴ ⁵, Zhongkai Wu 吴钟凯 ¹, Xiaoshun He 何晓顺 ³ ⁴ ⁵
¹ Department of Cardiac Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
中国 广州 中山大学附属第一医院心脏外科
² Department of Extracorporeal Circulation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
中国 广州 中山大学附属第一医院体外循环科
³ Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
中国 广州 中山大学附属第一医院器官移植中心
⁴ Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), Guangzhou 510080, China
中国 广州 广东省器官移植国际科技合作基地
⁵ Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Guangzhou 510080, China
中国 广州 广东省器官捐献与移植免疫重点实验室
⁶ Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
中国 广州 中山大学附属第一医院麻醉科
⁷ Department of Cardiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
中国 广州 中山大学附属第一医院心内科
⁸ Department of Neurosurgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
中国 广州 中山大学附属第一医院神经外科
⁹ Operating Room and Anesthesia Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
中国 广州 中山大学附属第一医院手术室及麻醉中心
¹⁰ Cardiac Surgery Intensive Care Unit, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China
中国 广州 中山大学附属第一医院心脏重症监护室
¹¹ Organ Transplantation Center, The First Affiliated Hospital of the University of Science and Technology of China, Hefei 230001, China
中国 合肥 中国科学技术大学附属第一医院器官移植中心
¹² Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
ChinaXiv, 2021-10-02
Abstract

Ischemia and reperfusion injury (IRI), an inevitable component in organ transplantation, contributes to inferior graft survival, compromised organ quality and limitations in organ availability. The heart is most vulnerable to IRI and tolerated ischemic times are very short. We present an entire novel heart transplant procedure during which the donor heart was continuously perfused, oxygenated at normothermia and transplanted while beating.

The dynamic electrocardiogram and echocardiogram indicated an absence of ischemic injury and excellent function of the donor heart during the entire procedure. This ischemia-free beating heart transplantation (IFBHT) avoids graft IRI. The approach has thus the potential to improve transplant outcome while improving organ utilization.
Transplantation of a Beating Heart: A First in Human_1
Transplantation of a Beating Heart: A First in Human_2
Transplantation of a Beating Heart: A First in Human_3
  • Advanced applications of pulsed laser deposition in electrocatalysts for hydrogen-electric conversion systems
  • Yuanyuan Zhou, Yong Wang, Ke Zhang, Huaqian Leng, Peter Müller-Buschbaum, Nian Li, Liang Qiao
  • Opto-Electronic Advances
  • 2025-11-25
  • A review on optical torques: from engineered light fields to objects
  • Tao He, Jingyao Zhang, Din Ping Tsai, Junxiao Zhou, Haiyang Huang, Weicheng Yi, Zeyong Wei Yan Zu, Qinghua Song, Zhanshan Wang, Cheng-Wei Qiu, Yuzhi Shi, Xinbin Cheng
  • Opto-Electronic Science
  • 2025-11-25
  • IncepHoloRGB: multi-wavelength network model for full-color 3D computer-generated holography
  • Xuan Yu, Zhilin Teng, Xuhao Fan, Tianchi Liu, Wenbin Chen, Xinger Wang, Zhe Zhao, Wei Xiong, Hui Gao
  • Opto-Electronic Advances
  • 2025-10-25
  • Dual-band-tunable all-inorganic Zn-based metal halides for optical anti-counterfeiting
  • Meng Wang, Dehai Liang1, Saif M. H. Qaid, Shuangyi Zhao, Yingjie Liu, Zhigang Zang
  • Opto-Electronic Advances
  • 2025-10-25
  • Superchirality induced ultrasensitive chiral detection in high-Q optical cavities
  • Tianxu Jia, Youngsun Jeon Lv Feng Hongyoon Kim, Bingjue Li, Guanghao Rui, Junsuk Rho
  • Opto-Electronic Advances
  • 2025-10-25
  • Unsupervised learning enabled label-free single-pixel imaging for resilient information transmission through unknown dynamic scattering media
  • Fujie Li, Haoyu Zhang, Zhilan Lu, Li Yao, Yuan Wei, Ziwei Li, Feng Bao, Junwen Zhang, Yingjun Zhou, Nan Chi
  • Opto-Electronic Advances
  • 2025-10-25
  • Simultaneous detection of inflammatory process indicators via operando dual lossy mode resonance-based biosensor
  • Desiree Santano, Abian B. Socorro, Ambra Giannetti, Ignacio Del Villar, Francesco Chiavaioli
  • Opto-Electronic Science
  • 2025-10-16
  • Noncommutative metasurfaces enabled diverse quantum path entanglement of structured photons
  • Yan Wang, Yichang Shou, Jiawei Liu, Qiang Yang, Shizhen Chen, Weixing Shu, Shuangchun Wen, Hailu Luo
  • Opto-Electronic Science
  • 2025-10-16
  • Halide perovskite volatile unipolar nanomemristor
  • Abolfazl Mahmoodpoor, Prokhor A. Alekseev, Ksenia A. Gasnikova, Kuzmenko Natalia, Artem Larin, Sergey Makarov Aleksandra Furasova
  • Opto-Electronic Advances
  • 2025-10-15
  • Recent advances in exciton-polariton in perovskite
  • Khalil As'ham, Andergachew Mekonnen Berhe, Ibrahim A. M. Al-Ani, Haroldo T. Hattori, Andrey E. Miroshnichenko
  • Opto-Electronic Science
  • 2025-09-25
  • Harmonic heterostructured pure Ti fabricated by laser powder bed fusion for excellent wear resistance via strength-plasticity synergy
  • Desheng Li, Huanrong Xie, Chengde Gao, Huan Jiang, Liyuan Wang, Cijun Shuai
  • Opto-Electronic Advances
  • 2025-09-25
  • Strong-confinement low-index-rib-loaded waveguide structure for etchless thin-film integrated photonics
  • Yifan Qi, Gongcheng Yue, Ting Hao, Yang Li
  • Opto-Electronic Advances
  • 2025-09-25



  • Detecting subtle yet fast skeletal muscle contractions with ultrasoft and durable graphene-based cellular materials                                Age and composition of young basalts on the Moon, measured from samples returned by Chang'e-5
    About
    |
    Contact
    |
    Copyright © PubCard