Year
Month
(Peer-Reviewed) Chiral detection of biomolecules based on reinforcement learning
Yuxiang Chen 陈宇翔 ¹, Fengyu Zhang 张凤宇 ² ⁴, Zhibo Dang 党郅博 ¹, Xiao He 何霄 ¹, Chunxiong Luo 罗春雄 ² ⁴, Zhengchang Liu 刘正昌 ³, Pu Peng 彭璞 ¹, Yuchen Dai 戴宇琛 ³, Yijing Huang 黄逸婧 ¹, Yu Li 李瑜 ³, Zheyu Fang 方哲宇 ¹ ³
¹ School of Physics, Peking University, Beijing 100871, China
中国 北京 北京大学物理学院
² The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics & Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
中国 北京 北京大学 前沿交叉学科研究院 定量生物学中心 物理学院 人工微结构和介观物理国家重点实验室
³ Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
中国 北京 北京大学 前沿交叉学科研究院
⁴ Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, China
中国 温州 中国科学院大学温州研究院
Opto-Electronic Science, 2023-02-09
Abstract

Chirality plays an important role in biological processes, and enantiomers often possess similar physical properties and different physiologic functions. In recent years, chiral detection of enantiomers become a popular topic.

Plasmonic metasurfaces enhance weak inherent chiral effects of biomolecules, so they are used in chiral detection. Artificial intelligence algorithm makes a lot of contribution to many aspects of nanophotonics. Here, we propose a nanostructure design method based on reinforcement learning and devise chiral nanostructures to distinguish enantiomers.

The algorithm finds out the metallic nanostructures with a sharp peak in circular dichroism spectra and emphasizes the frequency shifts caused by nearfield interaction of nanostructures and biomolecules. Our work inspires universal and efficient machine-learning methods for nanophotonic design.
Chiral detection of biomolecules based on reinforcement learning_1
Chiral detection of biomolecules based on reinforcement learning_2
Chiral detection of biomolecules based on reinforcement learning_3
  • Light-induced enhancement of exciton transport in organic molecular crystal
  • Xiao-Ze Li, Shuting Dai, Hong-Hua Fang, Yiwen Ren, Yong Yuan, Jiawen Liu, Chenchen Zhang, Pu Wang, Fangxu Yang, Wenjing Tian, Bin Xu, Hong-Bo Sun
  • Opto-Electronic Advances
  • 2025-03-28
  • Double topological phase singularities in highly absorbing ultra-thin film structures for ultrasensitive humidity sensing
  • Xiaowen Li, Jie Sheng, Zhengji Wen, Fangyuan Li, Xiran Huang, Mingqing Zhang, Yi Zhang, Duo Cao2, Xi Shi, Feng Liu, Jiaming Hao
  • Opto-Electronic Advances
  • 2025-03-28
  • Soliton microcombs in optical microresonators with perfect spectral envelopes
  • Mulong Liu, Ziqi Wei, Haotong Zhu, Hongwei Wang, Xiao Yu, Xilin Han, Wei Zhao, Guangwei Hu, Peng Xie
  • Opto-Electronic Advances
  • 2025-03-12
  • Terahertz active multi-channel vortices with parity symmetry breaking and near/far field multiplexing based on a dielectric-liquid crystal-plasmonic metadevice
  • Yiming Wang, Fei Fan, Huijun Zhao, Yunyun Ji, Jing Liu, Shengjiang Chang
  • Opto-Electronic Advances
  • 2025-03-06
  • Spin-dependent amplitude and phase modulation with multifold interferences via single-layer diatomic all-silicon metasurfaces
  • Hui Li, Chenhui Zhao, Jie Li, Hang Xu, Wenhui Xu, Qi Tan, Chunyu Song, Yun Shen, Jianquan Yao
  • Opto-Electronic Science
  • 2025-02-19
  • Highly sensitive laser spectroscopy sensing based on a novel four-prong quartz tuning fork
  • Runqiu Wang, Shunda Qiao, Ying He, Yufei Ma
  • Opto-Electronic Advances
  • 2025-01-22
  • A novel approach towards robust construction of physical colors on lithium niobate crystal
  • Quanxin Yang, Menghan Yu, Zhixiang Chen, Siwen Ai, Ulrich Kentsch, Shengqiang Zhou, Yuechen Jia, Feng Chen, Hongliang Liu
  • Opto-Electronic Advances
  • 2025-01-22
  • Multi-photon neuron embedded bionic skin for high-precision complex texture and object reconstruction perception research
  • Hongyu Zhou, Chao Zhang, Hengchang Nong, Junjie Weng, Dongying Wang, Yang Yu, Jianfa Zhang, Chaofan Zhang, Jinran Yu, Zhaojian Zhang, Huan Chen, Zhenrong Zhang, Junbo Yang
  • Opto-Electronic Advances
  • 2025-01-22
  • Single-beam optical trap-based surface-enhanced raman scattering optofluidic molecular fingerprint spectroscopy detection system
  • Ning Sun, Yuan Gan, Yujie Wu, Xing Wang, Shen Shen, Yong Zhu, Jie Zhang
  • Opto-Electronic Advances
  • 2025-01-22
  • High-frequency enhanced ultrafast compressed active photography
  • Yizhao Meng, Yu Lu, Pengfei Zhang, Yi Liu, Fei Yin, Lin Kai, Qing Yang, Feng Chen
  • Opto-Electronic Advances
  • 2025-01-15
  • Efficient generation of vectorial terahertz beams using surface-wave excited metasurfaces
  • Zhuo Wang, Weikang Pan, Yu He, Zhiyan Zhu, Xiangyu Jin, Muhan Liu, Shaojie Ma, Qiong He, Shulin Sun, Lei Zhou
  • Opto-Electronic Science
  • 2025-01-15
  • High-efficiency RGB achromatic liquid crystal diffractive optical elements
  • Yuqiang Ding, Xiaojin Huang, Yongziyan Ma, Yan Li, Shin-Tson Wu
  • Opto-Electronic Advances
  • 2025-01-07



  • Periodic transparent nanowires in ITO film fabricated via femtosecond laser direct writing                                Comparative analysis of NovaSeq 6000 and MGISEQ 2000 single-cell RNA sequencing data
    About
    |
    Contact
    |
    Copyright © PubCard