Year
Month
(Peer-Reviewed) Chiral detection of biomolecules based on reinforcement learning
Yuxiang Chen 陈宇翔 ¹, Fengyu Zhang 张凤宇 ² ⁴, Zhibo Dang 党郅博 ¹, Xiao He 何霄 ¹, Chunxiong Luo 罗春雄 ² ⁴, Zhengchang Liu 刘正昌 ³, Pu Peng 彭璞 ¹, Yuchen Dai 戴宇琛 ³, Yijing Huang 黄逸婧 ¹, Yu Li 李瑜 ³, Zheyu Fang 方哲宇 ¹ ³
¹ School of Physics, Peking University, Beijing 100871, China
中国 北京 北京大学物理学院
² The State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics & Center for Quantitative Biology, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
中国 北京 北京大学 前沿交叉学科研究院 定量生物学中心 物理学院 人工微结构和介观物理国家重点实验室
³ Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
中国 北京 北京大学 前沿交叉学科研究院
⁴ Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, China
中国 温州 中国科学院大学温州研究院
Opto-Electronic Science, 2023-02-09
Abstract

Chirality plays an important role in biological processes, and enantiomers often possess similar physical properties and different physiologic functions. In recent years, chiral detection of enantiomers become a popular topic.

Plasmonic metasurfaces enhance weak inherent chiral effects of biomolecules, so they are used in chiral detection. Artificial intelligence algorithm makes a lot of contribution to many aspects of nanophotonics. Here, we propose a nanostructure design method based on reinforcement learning and devise chiral nanostructures to distinguish enantiomers.

The algorithm finds out the metallic nanostructures with a sharp peak in circular dichroism spectra and emphasizes the frequency shifts caused by nearfield interaction of nanostructures and biomolecules. Our work inspires universal and efficient machine-learning methods for nanophotonic design.
Chiral detection of biomolecules based on reinforcement learning_1
Chiral detection of biomolecules based on reinforcement learning_2
Chiral detection of biomolecules based on reinforcement learning_3
  • Video-rate wavefront capture and replay via single-shot reference-free measurement: toward holographic telepresence
  • Minwook Kim, Chansuk Park, Chulmin Oh, KyeoReh Lee, Herve Hugonnet, YongKeun Park
  • Opto-Electronic Advances
  • 2026-08-25
  • Luminescent YAG:Ce³⁺ 3D micro-structures via multi-photon laser lithography
  • Robertas Virkėtis, Greta Merkininkaitė, Artūr Harnik, Ugnė Ūsaitė, Dominykas Dapšys, Arturo Susarrey-Arce, Simas Šakirzanovas, Mangirdas Malinauskas
  • Opto-Electronic Advances
  • 2026-08-25
  • A 36 × 240 Gbps hybrid mode/wavelength division multiplexing transmitter using lithium niobate on insulator
  • Mingyu Zhu, Weihan Wang, Ruitao Ma, Aoyun Gao, Chun Gao, Zexu Wang, Fei Huang, Zhenyuan Bao, Dajian Liu, Jiaxuan Gan, Zejie Yu, Huan Li, Weike Zhao, Daoxin Dai
  • Opto-Electronic Advances
  • 2026-08-25
  • Scalable spatiotemporal interleaving network for high-density integrated photonic convolution
  • Hudi Liu, Jingchi Li, Hua Zhong, Yu He, Yikai Su
  • Opto-Electronic Science
  • 2026-07-24
  • From non-resonant to resonant meta-devices: imaging, color routing, displaying, and beyond
  • Weihan Liu, Yao Liang, Borui Leng, Shufan Chen, Peng-Yi Feng, Din Ping Tsai
  • Opto-Electronic Science
  • 2026-07-24
  • Light-perception-based interactive control of an underwater digital twin hand
  • Jinlong Lu, Chao Zhang, Hengchang Nong, Dongying Wang, Hongyu Zhou, Junjie Weng, Yuehua Deng, Yang Yu, Qiang Bian, Jianfa Zhang, Chaofan Zhang, Zhenrong Zhang, Junbo Yang
  • Opto-Electronic Advances
  • 2026-07-10
  • Digital twin optical computing system
  • Run Sun, Yuemin Li, Tingzhao Fu, Wencan Liu, Sigang Yang, Hongwei Chen
  • Opto-Electronic Advances
  • 2026-07-10
  • Unlocking home-based nocturnal health management: A fiber-optic approach for early detection of cardiorespiratory rhythm disorders
  • Hanyu Jin, Hao Li, Zhuolin Chen, Liangye Li, Zurui Wang, Kai Zhou, Weijian Hang, Zhipeng Chen, Junfeng Chen, Kai Shen, Jianfeng Wen, Chen Chen, Cunzheng Fan, Zhijun Yan, Feng Wang, Qizhen Sun
  • Opto-Electronic Advances
  • 2026-07-10
  • A flexible wireless system for prospective photodynamic therapy applications
  • Rolan Mansour, Bhavani Yalagala, Vikas Vikas, Nikolas Bruce, Fawziye Tarhini, Georgios N. Arvanitakis, Mohammed Mughal, Jamie Blanche, Ahmad Taha, Jonathan Copper, Muhammad Imran, Karin Williams, Karin Oien, Mahmoud Wagih, Hadi Heidari, Robert Hadfield, David Flynn
  • Opto-Electronic Advances
  • 2026-07-10
  • Parallel bright-field and multi-order edge imaging via wide field-of-view trichannel metalens
  • Xiaotong Li, Yeseul Kim, Youngsun Jeon, Junhwa Seong, Jaekyung Kim, Peng Tang, Shiqi Hu, Harit Keawmuang, Beomha Yang, Dongmin Jeon, Le Dai, Weiyan Li, Xiaodong Cai, Jinhui Shi, Yong-Sang Ryu, Trevon Badloe, Junsuk Rho
  • Opto-Electronic Advances
  • 2026-07-10
  • Cavity-assisted nonlocal metasurfaces for momentum-space broadband-operational optical vortice generation with maximum efficiency approaching 80%
  • Keren Wang, Kaili Sun, Jing Du, Peijuan Dai, Hao Zhou, Lujun Huang, Zhanghua Han, Wei Wang
  • Opto-Electronic Advances
  • 2026-07-10
  • Instantaneous UAV tracking using single-photon LiDAR via photon-event-driven suppression of temporal-averaging bias
  • Dongfang Guo, Jianfeng Sun, Xin Zhou, Chen Shen, Sheng Chen, Sining Li, Yanchen Qu
  • Opto-Electronic Technology
  • 2026-06-28



  • Periodic transparent nanowires in ITO film fabricated via femtosecond laser direct writing                                Comparative analysis of NovaSeq 6000 and MGISEQ 2000 single-cell RNA sequencing data
    About
    |
    Contact
    |
    Copyright © PubCard