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(Peer-Reviewed) Tunable phosphorene modulators – accelerating medical diagnosis with ultra-efficient photonic platforms
Yi Liu 刘轶 ¹, Huide Wang 王慧德 ¹, Honghai Zhu 朱宏海 ¹, Yihan Zhu 诸奕含 ¹, Wenkai Wang 王文凯 ¹, Haiyan Huang 黄海艳 ¹, Ziqian Wang 王子谦 ¹ ⁴, Yanqi Ge 葛彦奇 ¹, Songrui Wei 魏松瑞 ¹, Yong Liu 刘永 ¹, Guoqing Liu 刘国卿 ¹, Liping Liu 刘利平 ², Wei Chi 迟玮 ³, Weihua Yang 杨卫华 ³, Xinqi Ma 马歆琪 ³, Jianqing Li 李建慶 ⁴, Han Zhang 张晗 ¹
¹ State Key Laboratory of Radio frequency Heterogeneous integration, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology, Institute for Advanced Study in Nuclear Energy & Safety, Shenzhen Key Laboratory of Nuclear and Radiation Safety, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China
中国 深圳 深圳大学物理与光电工程学院 深圳市核与辐射安全重点实验室 中国核能与安全高等研究院 二维材料光电科技国际合作联合实验室 射频异质异构集成全国重点实验室
² Shenzhen People’s Hospital, Shenzhen 518060, China
中国 深圳 深圳市人民医院
³ Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, 18 Zetian Road, Futian District, Shenzhen 518060, China
中国 深圳 深圳市眼科医院 南方医科大学深圳眼科医学中心
⁴ School of Computer Science and Engineering, Macau University of Science and Technology, Macau 999078, China
中国 澳门 澳门科技大学 计算机科学与工程学院
Opto-Electronic Advances , 2026-05-29
Abstract

The rapid integration of deep learning in medical image diagnosis is challenged by the energy inefficiency and data bottlenecks of conventional electronic computing. Photonic Neural Networks (PNNs) offer a promising, ultra-parallel computing paradigm to overcome these limitations. In this work, we present a high-performance electro-optic modulator realized by synergizing the exceptional properties of a phosphorene-based van der Waals heterostructure with the enhanced light-matter interaction of a microring resonator.

This design achieves efficient, low-power modulation with a high modulation efficiency of 0.25 V·cm. We utilized this modulator to construct a prototype all-fiber PNN based on a time-division multiplexing architecture. To improve computational precision, we employed a Ring-Assisted Mach–Zehnder Interferometer (RAMZI) structure, effectively extending the linear operating region for precise weight matrix representation.

Experimental validation confirms the PNN’s robust and accurate performance in complex tasks, including handwritten digit classification, retinal B-scan analysis, and multiphase liver CT image diagnosis. This study introduces a high-efficiency electro-optic modulation scheme and lays the foundation for highly integrated, low-power, fiber-based PNNs for accelerated and efficient medical diagnostics.
Tunable phosphorene modulators – accelerating medical diagnosis with ultra-efficient photonic platforms_1
Tunable phosphorene modulators – accelerating medical diagnosis with ultra-efficient photonic platforms_2
Tunable phosphorene modulators – accelerating medical diagnosis with ultra-efficient photonic platforms_3
Tunable phosphorene modulators – accelerating medical diagnosis with ultra-efficient photonic platforms_4
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